Effects of myo-inositol plus alpha-lactalbumin in myo-inositol-resistant PCOS women

Myo-Inositol in the Treatment of Teenagers Affected by PCOS

Objective. To compare the effectiveness of myo-inositol (MI) and oral contraceptive pills (OCPs) in monotherapy and MI in combination with OCPs in the treatment of teenagers affected by polycystic ovary syndrome (PCOS). Methods. 61 adolescent girls aged 13-19 years, with PCOS, were involved in the prospective, open-label study. Patients were randomized into three groups: I group, 20 patients re...

Role of myo-inositol

myo-Inositol phosphorothioates, phosphatase-resistant analogues

Syntheses of a metabolite of the second messenger myo-inositol 1,4,5-trisphosphate, myo-inositol 1,4bisphosphate, and an analogue, the 1,4-bisphosphorothioate, are reported, by using phosphite chemistry on (± )1,2: 4,5-di-isopropylidene-myo-inositol. The synthesis of (± )1,2: 4,5-di-isopropylidene 3,6-bis[di-(2cyanoethyl)]phosphite provides an intermediate that can be oxidized to either the cor...

Myo-inositol effects in women with PCOS: a meta-analysis of randomized controlled trials

Myo-inositol (MI) supplementation in women with polycystic ovary syndrome (PCOS) has been evaluated over the last years. Many hormonal and reproductive impairments associated with this disorder seem relieved by the supplement. The objective of the meta-analysis was to assess the effects of MI alone or combined with d-chiro-inositol (DCI) on the endocrine and metabolic abnormalities of women wit...

myo-Inositol metabolism in plants

The multifunctional position supplied by myo-inositol is emerging as a central feature in plant biochemistry and physiology. In this critique, attention is drawn to metabolic aspects and current assessment is made of manifold ways in which myo-inositol and its metabolic products impact growth and development. The fact that a unique enzyme, common to all eukaryotic organisms where such assessmen...